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Behind the Scenes at the Cocktail Laboratory Shaping Colombia’s Spirits: A World’s 50 Best Bar Experience

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In Medellín, Colombia, Mamba Negra, recognized as one of the World’s 50 Best Bars, has introduced an innovative experience called Mamba Lab. Nestled within an unassuming building high in the hills, Mamba Lab is described as a cocktail laboratory where a passion for mixology transforms into a scientific endeavor. With its high-tech machinery and vibrant décor, it sets the stage for an immersive exploration of Colombian ingredients.

Mamba Lab debuted as part of the efforts of Mamba Negra, which opened in 2022 and has since shaped Medellín’s cocktail scene. The unique cocktail tasting menu features eight mini cocktails, each showcasing locally sourced ingredients. Every product used in the cocktails, from spirits to garnishes, is 100% Colombian, highlighting the country’s rich biodiversity.

Mamba Negra’s founder, Juan David Zapata, emphasized the potential of Colombian ingredients in crafting extraordinary drinks. “Colombia has nothing to envy when it comes to what we can offer,” he stated, underscoring the country’s vast natural resources.

The innovative cocktails crafted in Mamba Lab utilize ingredients such as a Colombian-made vermouth derived from native herbs, a wine made from local purple yams, and custom distillates from local peppers. The menu is designed as a journey across Colombia with cocktails inspired by the minerals native to various regions.

Transforming Mamba Lab into a functioning laboratory took around nine months and was crucial to bringing Zapata’s vision to life. Both house-made and locally sourced spirits from traditional producers are utilized, emphasizing a commitment to celebrating Colombia’s cocktail culture.

With pride in their creation, the Mamba Negra team aims to elevate the perception of Colombian spirits, which have often faced stigma. The anticipation surrounding Mamba Lab extends beyond Medellín, as Zapata and his team recently showcased their creations in Italy through guest bartending events.

Ahead of its one-year anniversary, Mamba Lab is set to launch a new menu inspired by Colombia’s flowers during the upcoming Medellín Cocktail Week, an event designed to highlight Colombia’s burgeoning cocktail innovation. The festival will feature guest bartenders from renowned bars worldwide, further establishing Colombia as a competitive player in the global cocktail scene.

As Juan David Zapata continues to lead this movement, he reflects on his journey from Comuna 13, once one of the most dangerous neighborhoods, to spearheading one of the country’s exciting culinary ventures. His dedication to featuring locally sourced ingredients not only showcases Colombia’s potential but also resonates with the spirit and resilience of the nation.

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April 24, 2026 Recipes
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